Heat generation and dissipation in RF heated magnetic nanoparticle assemblies

Nanoparticles have numerous uses in the medical field from drug delivery vectors to magnetic resonance imaging and hyperthermia for cancer treatment. Two examples where understanding heat transport in nanoparticle systems is critical are cancer hyperthermia and local control of biological processes via conjugated, remotely heated nanoparticles. In nanoparticle-based cancer hyperthermia,  AC electromagnetic fields in the radiofrequency (RF) range is used to heat up superparamagnetic nanoparticles loaded to cancerous tissue. We are investigating heat generation and dissipation in RF heated nanoparticle assemblies in order to understand the main parameters such as nanoparticle coating, concentration and cluster formation. In parallel, we are exploring the potential to actuate biological process at cellular level employing RF actuated magnetic particles.